The tragedy in Burma [Myanmar] is exacerbated by the fact that the military-controlled goverment that doesn't care much for its people. The latest count is projecting that as many as 100,000 people might have died as a result of the Cyclone. People are usually moved to do something in times like these. In addition to any local organized efforts, I tend to funnel people towards the International Disaster Emergency Service. They are an established organization that have preexisting connections in the region through whom to deliver aid. Their organization is large enough to be effective, but not so large as to claim large portions of gifts for stateside administration. In short, their oversight can be trusted.
Of course, try to keep these people in your prayers.